Click here for a complete list of Lisa Reynolds’ publications on Google Scholar.

Dynamic fates of dietary antigen-specific T helper cells in a model of early life oral tolerance

FitzPatrick RD, Przydatek AM, Gatti DG, Norton NJ, Lane JM, Moeller BE, Robinson AN, Reynolds LA

bioRxiv [pre-print] posted Sept 4 2025: https://doi.org/10.1101/2025.08.30.673288

 

Associations between helminth infection status and the composition and concentration of fecal bile acids in school-age children in Uganda

Norton NJ, Hand CMM, Rowel C, Adriko M, Cai P, McManus DP, Egwang TG#, Reynolds LA# (# co-corresponding)

Scientific Reports 2025: 15;25509

 

Thymic eosinophils: What are you doing here?

Gatti DM, Reynolds LA

Journal of Leukocyte Biology 2025: 117(4)qiaf001

A pathogenic role for IL-10 signalling in capillary stalling and cognitive impairment in type 1 diabetes

Sharma S, Cheema M, Reeson PL, Narayana K, Boghozian R, Cota AP, Brosschot TP, FitzPatrick RD, Körbelin J, Reynolds LA, Brown CE

Nature Metabolism 2024 Nov; 6(11): 2082-2099

 

Fecal microbiota transplantation from protozoa-exposed donors downregulates immune response in a germ-free mouse model, its nole in immune response and physiology of the intestine

Partida-Rodriguez O, Brown EM, Woodward SE, Cirstea M, Reynolds LA, Petersen C, Vogt SL, Peña-Diaz J, Thorson L, Arrieta MC, Hernandez EG, Rojas-Velazquez L, Moran P, Gonzalez-Rivas E, Serrano-Vazquez A, Perez-Juarez H, Torres J, Ximenez C, Finlay BB

PLoS One 2024 Oct; 19(10):e0312775

 

 

Eosinophils respond to, but are not essential for control of an acute Salmonella enterica serovar Typhimurium infection in mice

FitzPatrick RD, Noone JR, Cartwright RA, Gatti DM, Brosschot TP, Lane JM, Jensen EL, Kroker Kimber I, Reynolds LA

Infection and Immunity 2024 Sept: DOI https://doi.org/10.1128/iai.00325-24 

 

Syphilis and the host; multi-omic analysis of host celllular responses to Treponema pallidum provides novel insight into syphilis pathogenesis

Waugh S, Ranasinghe A, Gomez A, Houston S, Lithgow LV, Eshghi A, Fleetwood J, Conway KME, Reynolds LA, Cameron CE

Frontiers in Microbiology 2023 Sept: https://doi.org/10.3389/fmicb.2023.1254342

 

 

Chronic small intestinal helminth infection perturbs bile acid homoeostasis and disrupts bile acid signaling in the murine small intestine

Lane JM, Brosschot TP, Gatti DM, Gauthier CM, Lawrence KM, Pluzhnikova V, Reynolds LA

Frontiers in Parasitology 2023 June: https://doi.org/10.3389/fpara.2023.1214136

 

MHCII+CD80+ thymic eosinophils increase in abundance during neonatal development in mice and their accumulation is microbiota-dependent

Gatti DM, Gauthier CM, Moeller BE, FitzPatrick RD, Kennedy MHE, Pluzhnikova V, Conway KME, Smazynski J, Chow RL, Reynolds LA

Journal of Leukocyte Biology. 2023 Sep;114(3):223-236

 

Identification and functional characterization of peptides with antimicrobial activity from the syphilis spirochete, Treponema palidum

Houston S, Schovanek E, Conway KME, Mustafa S, Gomez A, Ramaswamy R, Haimour A, Boulanger MJ, Reynolds LA, Cameron C

Frontiers in Microbiology. 2022 May: https://doi.org/10.3389/fmicb.2022.888525

 

Small intestinal levels of the branched short-chain fatty acid isovalerate are elevated during infection with Heligmosomoides polygyrus and can promote helminth fecundity

Kennedy MHE, Brosschot TP, Lawrence KM, FitzPatrick RD, Lane JM, Mariene GM, Wasmuth JD, Reynolds LA

Infection and Immunity. 2021 Nov;89(12):e0022521 

Impaired host resistance to Salmonella during helminth co-infection is restored by anthelmintic treatment prior to bacterial challenge

Brosschot TP, Lawrence KM, Moeller BE, Kennedy MHE, FitzPatrick RD, Gauthier CM, Shin D, Gatti DM, Conway KME, Reynolds LA

PLoS Neglected Tropical Diseases. 2021 Jan;15(1):e0009052 

 

 

Littermate-controlled experiments reveal eosinophils are not essential for maintaining steady-state IgA and demonstrate the influence of rearing conditions on antibody phenotypes in eosinophil-deficient mice

FitzPatrick RD, Kennedy MHE, Lawrence KM, Gauthier CM, Moeller BE, Robinson AN, Reynolds LA

Frontiers in Immunology. 2020 Oct;11:2528 

 

Microfluidic shear processing control of biological reduction stimuli-responsive polymer nanoparticles for drug delivery

Huang Y, Moini Jazani A, Howell EP, Reynolds LA, Kwon Oh J, Moffitt MG

ACS Biomaterials Science & Engineering. 2020 Jul 6(9):5069-5083

The impact of a helminth-modified microbiome on host immunity

Brosschot TP, Reynolds LA

Mucosal Immunol. 2018 Jul;11(4):1039-1046 Free full text

 

Asymptomatic intestinal colonization with protist Blastocystis is strongly associated with distinct microbiome ecological patterns

Nieves-Ramírez M, Partida-Rodríguez O, Laforest-Lapointe I, Reynolds LA, Brown E, Valdez-Salazar A, Morán-Silva P, Rojas L, Morien E, Parfrey LW, Minglian J, Walter J, Torres J, Arrieta MC, Ximénez-García C, Finlay BB

mSystems. 2018 Jun 26;3(3). pii: e00007-18.

 

Microbiome-driven allergic lung inflammation is ameliorated by short-chain fatty acids

Cait A, Hughes MR, Antignano F, Cait J, Dimitriu PA, Maas KR, Reynolds LA, Hacker L, Mohr J, Finlay BB, Zaph C, McNagny KM, Mohn WW.

Mucosal Immunol. 2018 May;11(3):785-795.

 

Functional specialization of intestinal dendritic cell subsets during Th2 helminth infection

Redpath SA, Heieis GA, Reynolds LA, Fonseca NM, Kim SS, Perona-Wright G.

Eur J Immunol. 2018 Jan;48(1):87-98

 

Early life factors that affect allergy development.

Reynolds LA, Finlay BB.

Nat Rev Immunol. 2017 Aug;17(8):518-528.

 

Enteric Helminths Promote Salmonella Coinfection by Altering the Intestinal Metabolome.

Reynolds LA, Redpath SA, Yurist-Doutsch S, Gill N, Brown EM, van der Heijden J, Brosschot TP, Han J, Marshall NC, Woodward SE, Valdez Y, Borchers CH, Perona-Wright G, Finlay BB.

J Infect Dis. 2017 Apr 15;215(8):1245-1254.

 

Salmonella Rapidly Regulates Membrane Permeability To Survive Oxidative Stress.

van der Heijden J, Reynolds LA, Deng W, Mills A, Scholz R, Imami K, Foster LJ, Duong F, Finlay BB.

MBio. 2016 Aug 9;7(4).

 

Analysis of bacterial survival after exposure to reactive oxygen species or antibiotics.

van der Heijden J, Vogt SL, Reynolds LA, Peña-Díaz J, Tupin A, Aussel L, Finlay BB.

Data Brief. 2016 Mar 22;7:894-9.

 

Exploring the redox balance inside gram-negative bacteria with redox-sensitive GFP.

van der Heijden J, Vogt SL, Reynolds LA, Peña-Díaz J, Tupin A, Aussel L, Finlay BB.

Free Radic Biol Med. 2016 Feb;91:34-44.

 

Worming Their Way into the Picture: Microbiota Help Helminths Modulate Host Immunity.

Reynolds LA, Finlay BB.

Immunity. 2015 Nov 17;43(5):840-2.

 

Cohabitation in the Intestine: Interactions among Helminth Parasites, Bacterial Microbiota, and Host Immunity.

Reynolds LA, Finlay BB, Maizels RM.

J Immunol. 2015 Nov 1;195(9):4059-66.

 

A Highly Effective Component Vaccine against Nontyphoidal Salmonella enterica Infections.

Ferreira RB, Valdez Y, Coombes BK, Sad S, Gouw JW, Brown EM, Li Y, Grassl GA, Antunes LC, Gill N, Truong M, Scholz R, Reynolds LA, Krishnan L, Zafer AA, Sal-Man N, Lowden MJ, Auweter SD, Foster LJ, Finlay BB.

MBio. 2015 Sep 22;6(5):e01421-15.

 

Diet and specific microbial exposure trigger features of environmental enteropathy in a novel murine model.

Brown EM, Wlodarska M, Willing BP, Vonaesch P, Han J, Reynolds LA, Arrieta MC, Uhrig M, Scholz R, Partida O, Borchers CH, Sansonetti PJ, Finlay BB.

Nat Commun. 2015 Aug 4;6:7806.

 

Concerted activity of IgG1 antibodies and IL-4/IL-25-dependent effector cells trap helminth larvae in the tissues following vaccination with defined secreted antigens, providing sterile immunity to challenge infection.

Hewitson JP, Filbey KJ, Esser-von Bieren J, Camberis M, Schwartz C, Murray J, Reynolds LA, Blair N, Robertson E, Harcus Y, Boon L, Huang SC, Yang L, Tu Y, Miller MJ, Voehringer D, Le Gros G, Harris N, Maizels RM.

PLoS Pathog. 2015 Mar 27;11(3):e1004676.

 

The hygiene hypothesis: current perspectives and future therapies.

Stiemsma LT, Reynolds LA, Turvey SE, Finlay BB.

Immunotargets Ther. 2015 Jul 27;4:143-57.

 

Direct measurement of oxidative and nitrosative stress dynamics in Salmonella inside macrophages.

van der Heijden J, Bosman ES, Reynolds LA, Finlay BB.

Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):560-5.

 

Perinatal antibiotic-induced shifts in gut microbiota have differential effects on inflammatory lung diseases.

Russell SL, Gold MJ, Reynolds LA, Willing BP, Dimitriu P, Thorson L, Redpath SA, Perona-Wright G, Blanchet MR, Mohn WW, Finlay BB, McNagny KM.

J Allergy Clin Immunol. 2015 Jan;135(1):100-9.

 

Commensal-pathogen interactions in the intestinal tract: lactobacilli promote infection with, and are promoted by, helminth parasites.

Reynolds LA, Smith KA, Filbey KJ, Harcus Y, Hewitson JP, Redpath SA, Valdez Y, Yebra MJ, Finlay BB, Maizels RM.

Gut Microbes. 2014 Jul 1;5(4):522-32.

 

MyD88 signaling inhibits protective immunity to the gastrointestinal helminth parasite Heligmosomoides polygyrus.

Reynolds LA, Harcus Y, Smith KA, Webb LM, Hewitson JP, Ross EA, Brown S, Uematsu S, Akira S, Gray D, Gray M, MacDonald AS, Cunningham AF, Maizels RM.

J Immunol. 2014 Sep 15;193(6):2984-93.

 

A case for antibiotic perturbation of the microbiota leading to allergy development.

Reynolds LA, Finlay BB.

Expert Rev Clin Immunol. 2013 Nov;9(11):1019-30.

 

Immunity to the model intestinal helminth parasite Heligmosomoides polygyrus.

Reynolds LA, Filbey KJ, Maizels RM.

Semin Immunopathol. 2012 Nov;34(6):829-46.

 

Cutting edge: in the absence of TGF-β signaling in T cells, fewer CD103+ regulatory T cells develop, but exuberant IFN-γ production renders mice more susceptible to helminth infection.

Reynolds LA, Maizels RM.

J Immunol. 2012 Aug 1;189(3):1113-7.

 

Immune modulation and modulators in Heligmosomoides polygyrus infection.

Maizels RM, Hewitson JP, Murray J, Harcus YM, Dayer B, Filbey KJ, Grainger JR, McSorley HJ, Reynolds LA, Smith KA.

Exp Parasitol. 2012 Sep;132(1):76-89.

 

Reactivation of suppressed RhoB is a critical step for the inhibition of anaplastic thyroid cancer growth.

Marlow LA, Reynolds LA, Cleland AS, Cooper SJ, Gumz ML, Kurakata S, Fujiwara K, Zhang Y, Sebo T, Grant C, McIver B, Wadsworth JT, Radisky DC, Smallridge RC, Copland JA.Cancer Res. 2009 Feb 15;69(4):1536-44.