{"id":243,"date":"2024-02-21T21:29:58","date_gmt":"2024-02-21T21:29:58","guid":{"rendered":"https:\/\/onlineacademiccommunity.uvic.ca\/mannersgroup\/?page_id=243"},"modified":"2024-02-21T21:56:36","modified_gmt":"2024-02-21T21:56:36","slug":"crystallization-driven-self-assembly","status":"publish","type":"page","link":"https:\/\/onlineacademiccommunity.uvic.ca\/mannersgroup\/crystallization-driven-self-assembly\/","title":{"rendered":"Crystallization-Driven Self-Assembly"},"content":{"rendered":"

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Crystallization-Driven Self-Assembly<\/h1>\n

Our research group has been at the forefront of the development of “Living” Crystallization-Driven Self-Assembly (CDSA) of Block Copolymers and other building blocks such as planar \u03c0-stacking organic molecules and metallocycles to form well-defined colloidally-stable 1D and 2D materials with tunable dimensions, spatially controlled surface and core chemistries, and potential applications from information storage and nanoelectronics to biomedicine. A focus has been on polyferrocenylsilane block copolymers, which were developed in our group, but our more recent work has also involved block copolymers with crystallizable \u03c0-conjugated or biodegradable segments. Together with our collaborators, we are currently investigating the fundamentals of the fascinating living CDSA process and also a range of potential applications of the resulting phase-separated thin films and core-shell nanostructures (micelles) as nanowires, nanoscopic barcodes, self-assembled heterojunctions, catalysts, and as magnetic dot precursors and in drug\/gene delivery.<\/span><\/p>\n

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Selected Publications:<\/h2>\n
    \n
  1. Multidimensional Hierarchical Self-Assembly of Amphiphilic Cylindrical Block Comicelles<\/a>
    Qiu, H.; Hudson, Z.M.; Winnik, M.A.; Manners, I.
    Science<\/em>,\u00a0<\/span>2015<\/strong>,\u00a0<\/span>347<\/em>, 1329.<\/li>\n
  2. Uniform patchy and hollow rectangular platelet micelles from crystallizable polymer blends<\/a>
    Qiu, H.; Gao, Y.; Boott, C.E.; Gould, O.E.C.; Harniman, R.L.; Miles, M.J.; Webb, S.E.D.; Winnik, M.A., Manners, I.
    Science<\/em>,\u00a0<\/span>2016<\/strong>,\u00a0<\/span>352<\/em>, 697.<\/li>\n
  3. Two dimensional assemblies from crystallizable homopolymers with charged termini<\/a>
    He, X.; Hsiao, M-S.; Boott, C.E.; Harniman, R.L.; Nazemi, A.; Li, X.; Winnik, M.A.; Manners, I.
    Nat. Mater.<\/em>,\u00a0<\/span>2017<\/strong>,\u00a0<\/span>16<\/em>, 481.<\/li>\n
  4. Scalable and uniform 1D nanoparticles by synchronous polymerization, crystallization and self-assembly<\/a>
    Boott, C.E.; Gwyther, J.; Harniman, R.L.; Hayward, D.W.; Manners, I.
    Nat. Chem.<\/em>,\u00a0<\/span>2017<\/strong>,\u00a0<\/span>9<\/em>, 785.<\/li>\n
  5. Uniform electroactive fiber-like micelle nanowires for organic electronics<\/a>
    Li, X.; Wolanin, P.J.; MacFarlane, L.R.; Harniman, R.L.; Qian, J.; Gould, O.E.C.; Dane, T.G.; Rudin, J.; Cryan, M.J.; Schmaltz, T.; Frauenrath, H.; Winnik, M.A.; Faul, C.F.J.; Manners, I.
    Nat. Commun.<\/em>,\u00a0<\/span>2017<\/strong>,\u00a0<\/span>8<\/em>, 15909.<\/li>\n
  6. Long-range Exciton Transport in Conjugated Polymer Nanofibers Prepared by Seeded Growth<\/a>
    Jin, X.-H.; Price, M.B.; Finnegan, J.R.; Boott, C.E.; Richter, J.M.; Rao, A.; Menke, M.; Friend, R.H.; Whittell, G.R.; Manners, I.
    Science<\/em>,\u00a0<\/span>2018<\/strong>,\u00a0<\/span>360<\/em>, 897.<\/li>\n
  7. Tailored Multifunctional Micellar Brushes via Crystallization-Driven Growth from a Surface<\/a>
    Cai, J.; Li, C.; Kong, N.; Lu, Y.; Lin, G.; Wang, X.; Yao, Y.; Manners, I.; Qiu, H.
    Science<\/em>,\u00a0<\/span>2019<\/strong>,\u00a0<\/span>366<\/em>, 1095.<\/li>\n
  8. Cellular Uptake and Targeting of Low Dispersity, Dual Emissive, Segmented Block Copolymer Nanofibers<\/a>
    Street, S.; He, Y.; Jin, X.; Hodgson, L.; Verkade, P.; Manners, I.
    Chem. Sci.<\/em>,\u00a0<\/span>2020<\/strong>,\u00a0<\/span>11<\/em>, 8394.<\/li>\n
  9. Tailored Self-Assembled Photocatalytic Nanofibers for Visible-light Driven Hydrogen Production<\/a>
    Tian, J.; Zhang, Y.; He, Y.; Jin, X-H.; Pearce, S. Eloi, J-C.; Harniman, R.L.; Alibhai, D.; Ye, R.; Philiips, D.L.; Manners, I.
    Nat. Chem.<\/em>,\u00a0<\/span>2020<\/strong>,\u00a0<\/span>12<\/em>, 1150.<\/li>\n
  10. Scalable and Uniform Length-Tunable Biodegradable Block Copolymer Nanofibers with a Polycarbonate Core via Living Polymerization-Induced Crystallization-Driven Self-assembly<\/a>
    Ellis, C.E.; Hernandez, J.D.G.; Manners, I.
    J. Am. Chem. Soc.<\/em>,\u00a0<\/span>2022<\/strong>,\u00a0<\/span>144<\/em>, 20525.<\/li>\n
  11. Length-Controlled Nanofiber Micelleplexes as Efficient Nucleic Acid Delivery Vehicles<\/a>
    Street, S.T.G.; Chrenek, J.; Harniman, R.L.; Letwin, K.; Mantell, J.M.; Borucu, U.; Willerth, S.M.; Manners, I.
    J. Am. Chem. Soc.<\/em>,\u00a0<\/span>2022<\/strong>,\u00a0<\/span>144<\/em>, 19799.<\/li>\n
  12. High Resolution Cryo-Electron Microscopy Structure of Block Copolymer Nanofibers with a Crystalline Core<\/a>
    Tian, J.; Xie, S.-H.; Borucu, U.; Lei, S.; Zhang, Y.; Manners, I.
    Nat. Mater.<\/em>,\u00a0<\/span>2023<\/strong>,\u00a0<\/span>22<\/em>, 786.<\/li>\n
  13. Uniform Segmented Platelet Micelles with Compositionally Distinct and Selectively Degradable Cores<\/a>
    Tong, Z.; Xie, Y.; Arno, M.C.; Zhang, Y.; Manners, I.; O’Reilly, R.K.; Dove, A.P.
    Nat. Chem.<\/em>,\u00a0<\/span>2023<\/strong>,\u00a0<\/span>15<\/em>, 824.<\/li>\n
  14. Mechanism of Action and Design of Potent Antibacterial Block Copolymer Nanoparticles<\/a>
    Parkin, H.C.; Street, S.T.G.; Gowen, B.; Da-Silva-Correa, L.H.; Hof, R.; Buckley, H.L.; Manners, I.
    J. Am. Chem. Soc<\/em>, 2024<\/strong>, online<\/em>.<\/li>\n<\/ol>\n

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    Crystallization-Driven Self-Assembly Our research group has been at the forefront of the development of “Living” Crystallization-Driven Self-Assembly (CDSA) of Block Copolymers and other building blocks such as planar \u03c0-stacking organic molecules and metallocycles to form well-defined colloidally-stable 1D and 2D materials with tunable dimensions, spatially controlled surface and core chemistries, and potential applications from information […]<\/p>\n","protected":false},"author":19926,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-243","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/onlineacademiccommunity.uvic.ca\/mannersgroup\/wp-json\/wp\/v2\/pages\/243","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/onlineacademiccommunity.uvic.ca\/mannersgroup\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/onlineacademiccommunity.uvic.ca\/mannersgroup\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/onlineacademiccommunity.uvic.ca\/mannersgroup\/wp-json\/wp\/v2\/users\/19926"}],"replies":[{"embeddable":true,"href":"https:\/\/onlineacademiccommunity.uvic.ca\/mannersgroup\/wp-json\/wp\/v2\/comments?post=243"}],"version-history":[{"count":3,"href":"https:\/\/onlineacademiccommunity.uvic.ca\/mannersgroup\/wp-json\/wp\/v2\/pages\/243\/revisions"}],"predecessor-version":[{"id":258,"href":"https:\/\/onlineacademiccommunity.uvic.ca\/mannersgroup\/wp-json\/wp\/v2\/pages\/243\/revisions\/258"}],"wp:attachment":[{"href":"https:\/\/onlineacademiccommunity.uvic.ca\/mannersgroup\/wp-json\/wp\/v2\/media?parent=243"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}