{"id":2696,"date":"2021-12-20T14:25:17","date_gmt":"2021-12-20T22:25:17","guid":{"rendered":"https:\/\/onlineacademiccommunity.uvic.ca\/ialh\/?p=2696"},"modified":"2022-02-03T14:39:27","modified_gmt":"2022-02-03T22:39:27","slug":"engineering-brain-and-spinal-cord-tissue-constructs","status":"publish","type":"post","link":"https:\/\/onlineacademiccommunity.uvic.ca\/ialh\/engineering-brain-and-spinal-cord-tissue-constructs\/","title":{"rendered":"Engineering brain and spinal cord tissue constructs"},"content":{"rendered":"<p><strong>Publication Alert!<\/strong> IALH Affiliate Stephanie Willerth co-wrote an article entitled <span style=\"color: #00acce\"><em>Engineering brain and spinal cord tissue constructs<\/em><\/span> with Michel Modo and Kyle Lampe. It was published in <em>Brain Research Bulletin.<\/em><\/p>\n<p><strong>Introduction:<\/strong><\/p>\n<p>The engineering of neural tissues has been a quest for over 30 years and remains one of the most challenging endeavors for tissue engineering and regenerative medicine (<a class=\"workspace-trigger\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0361923021003336?via%3Dihub#bib5\" name=\"bbib5\">Kaul and Ventikos, 2015<\/a>). The isolation of neural stem cells (NSCs) provides a stable and reliable source of cells, including those of human origin, that can be expanded\u00a0<em>in vitro<\/em>\u00a0and differentiated into neurons, astrocytes and oligodendrocytes (<a class=\"workspace-trigger\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0361923021003336?via%3Dihub#bib1\" name=\"bbib1\">Breunig et al., 2011<\/a>). Researchers produce engineered 3D tissue constructs by combining this off-the-shelf cell source with biomaterials that provide structural and biochemical signaling components to developing cells. These constructs engineered for neural applications facilitate tightly controlled\u00a0<em>in vitro<\/em>\u00a0experiments, as well as represent transplantable products aimed at repairing damaged brain and\/or spinal cord tissues (<a class=\"workspace-trigger\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0361923021003336?via%3Dihub#bib9\" name=\"bbib9\">Willerth, 2017<\/a>). This special issue on\u00a0<em>Engineering of Brain and Spinal Cord Tissue Constructs<\/em>\u00a0presents a collection of primary research and review articles that chart state-of-the-art tissue engineering approaches to create de novo neural tissues.<\/p>\n<p>To read the full article, visit <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0361923021003336?via%3Dihub\">https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0361923021003336?via%3Dihub\u00a0<\/a><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Publication Alert! IALH Affiliate Stephanie Willerth co-wrote an article entitled Engineering brain and spinal cord tissue constructs with Michel Modo and Kyle Lampe. It was published in Brain Research Bulletin. Introduction: The engineering of neural tissues has been a quest for over 30 years and remains one of the most challenging endeavors for tissue engineering &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/onlineacademiccommunity.uvic.ca\/ialh\/engineering-brain-and-spinal-cord-tissue-constructs\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Engineering brain and spinal cord tissue constructs&#8221;<\/span><\/a><\/p>\n","protected":false},"author":8486,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[50,1],"tags":[60],"class_list":["post-2696","post","type-post","status-publish","format-standard","hentry","category-brain-health","category-health","tag-stephanie-willerth","entry"],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/onlineacademiccommunity.uvic.ca\/ialh\/wp-json\/wp\/v2\/posts\/2696","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/onlineacademiccommunity.uvic.ca\/ialh\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/onlineacademiccommunity.uvic.ca\/ialh\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/onlineacademiccommunity.uvic.ca\/ialh\/wp-json\/wp\/v2\/users\/8486"}],"replies":[{"embeddable":true,"href":"https:\/\/onlineacademiccommunity.uvic.ca\/ialh\/wp-json\/wp\/v2\/comments?post=2696"}],"version-history":[{"count":1,"href":"https:\/\/onlineacademiccommunity.uvic.ca\/ialh\/wp-json\/wp\/v2\/posts\/2696\/revisions"}],"predecessor-version":[{"id":2697,"href":"https:\/\/onlineacademiccommunity.uvic.ca\/ialh\/wp-json\/wp\/v2\/posts\/2696\/revisions\/2697"}],"wp:attachment":[{"href":"https:\/\/onlineacademiccommunity.uvic.ca\/ialh\/wp-json\/wp\/v2\/media?parent=2696"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/onlineacademiccommunity.uvic.ca\/ialh\/wp-json\/wp\/v2\/categories?post=2696"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/onlineacademiccommunity.uvic.ca\/ialh\/wp-json\/wp\/v2\/tags?post=2696"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}