IALH Research Fellow Brian Christie and IALH Student Affiliate Jamie Morrison have co-authored a new research article entitled Repeated mild traumatic brain injury causes sex-specific increases in cell proliferation and inflammation in juvenile rats. Collaborating authors include Katie J. Neale, Hannah M. O. Reid, Barbara Sousa, Erin McDonagh, Sandy Shultz, and Eric Eyolfson. The article …
Tag Archives: Microglia
Editorial: Insights on Neuroinflammatory Response by Microglia-Targeted Pharmacology
IALH Research Fellow Hector Caruncho has co-authored a new editorial article entitled Editorial: Insights on neuroinflammatory response by microglia-targeted pharmacology. Collaborating authors include Jacob Raber, Philippe De Deurwaerdere and Massimo Grilli. The article was published in Frontiers in Pharmacology. First Paragraph: Microglia, the innate immune cells of the CNS, are critical for the regulation of …
ARG1-Expressing Microglia Show a Distinct Molecular Signature and Modulate Postnatal Development and Function of the Mouse Brain
IALH Research Fellow Marie-Ève Tremblay co-authored a research article entitled ARG1-expressing microglia show a distinct molecular signature and modulate postnatal development and function of the mouse brain. Collaborating authors include Vassilis Stratoulias, Rocío Ruiz, Shigeaki Kanatani, Ahmed M. Osman, Lily Keane, Jose A. Armengol, Antonio Rodríguez-Moreno, Adriana-Natalia Murgoci, Irene García-Domínguez, Isabel Alonso-Bellido, Fernando González Ibáñez, …
Origin and Emergence of Microglia in the CNS—An Interesting (Hi)story of an Eccentric Cell
IALH Research Fellow Marie-Eve Tremblay (Division of Medical Sciences) has co-authored a new research article entitled Origin and Emergence of Microglia in the CNS—An Interesting (Hi)story of an Eccentric Cell. Collaborating authors include Iasonas Dermitzakis, Maria Eleni Manthou, Soultana Meditskou, Steven Petratos, Lida Zoupi, Marina Boziki, Evangelia Kesidou, Constantina Simeonidou, and Paschalis Theotokis. The article …
The Outcomes of Maternal Immune Activation Induced with the Viral Mimetic Poly I:C on Microglia in Exposed Rodent Offspring
IALH Research Fellow Marie-Ève Tremblay and IALH Student Affiliate Collin Murray have co-authored a new research article entitled The Outcomes of Maternal Immune Activation Induced with the Viral Mimetic Poly I:C on Microglia in Exposed Rodent Offspring. Collaborating authors include Sophia M. Loewen, Adriano M. Chavesa, Marianela E. Traetta, Sophia E. Burns, and Keelin H. …
Prenatal Inflammation Shapes Microglial Immune Response into Adulthood
Publication alert! IALH Research Fellow Marie-ÈveTremblay has co-authored a research article entitled Prenatal inflammation shapes microglial immune response into adulthood with Marianela E.Traetta. The article was published in Trends in Immunology. Abstract: Hayes and collaborators recently unraveled that maternal immune activation in mice led to a long-lasting decrease in microglial immune reactivity. Thus, microglia exhibited …
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Microglia in Human Postmortem Brain Samples: Quantitative Ultrastructural Analysis of Scanning Electron Microscopy Image
Publication alert! IALH Research Fellow Marie-Ève Tremblay has co-authored a new protocol entitled Microglia in Human Postmortem Brain Samples: Quantitative Ultrastructural Analysis of Scanning Electron Microscopy Images with collaborating authors Marie-Kim St-Pierre, Eva Šimončičová and Micaël Carrier. The protocol was published in Alzheimer’s Disease (pp 63–85). Abstract: In this protocol, we describe the specific steps …
The Missing Piece? A Case for Microglia’s Prominent Role in the Therapeutic Action of Anesthetics, Ketamine, and Psychedelics
Publication alert! IALH Research Fellow Eve Tremblay has co-authored a new research article entitled The Missing Piece? A Case for Microglia’s Prominent Role in the Therapeutic Action of Anesthetics, Ketamine, and Psychedelics. Collaborating authors include Jared VanderZwaag, Torin Halvorson, Kira Dolhan, Eva Šimončičová, and Benneth Ben-Azu. The article was published in Neurochemical Research. Abstract: There …
Microglial Homeostasis Disruption Modulates Non-Rapid Eye Movement Sleep Duration and Neuronal Activity in Adult Female Mice
Publication alert! IALH Research Fellow Marie-ÈveTremblay has co-authored a new research article entitled Microglial homeostasis disruption modulates non-rapid eye movement sleep duration and neuronal activity in adult female mice. Other authors include Katherine Picard, Giorgio Corsi, Fanny Decoeur, Maria Amalia Di Castro, Maude Bordeleau, Marine Persillet, Sophie Layé, Cristina Limatola, and Agnès Nadjar. The article …
Density of TMEM119-Positive Microglial Cells in Postmortem Cerebrospinal Fluid as a Surrogate Marker for Assessing Complex Neuropathological Processes in the CNS
Publication alert! IALH Research Fellow Marie-Ève Tremblay has co-authored a new research article entitled Density of TMEM119-positive microglial cells in postmortem cerebrospinal fluid as a surrogate marker for assessing complex neuropathological processes in the CNS. Other authors include Simone Bohnert, Stefanie Trella, Ulrich Preiß, Helmut Heinsen, Michael Bohnert, Johann Zwirner, Camelia-Maria Monoranu and Benjamin Ondruschka. …
Manual versus automatic analysis of microglial density and distribution: a comparison in the hippocampus of healthy and lipopolysaccharide-challenged mature male mice
Publication alert! IALH Research Fellow Marie-Ève Tremblay has co-authored a new research article entitled Manual versus automatic analysis of microglial density and distribution: a comparison in the hippocampus of healthy and lipopolysaccharide-challenged mature male mice. Other authors include Mohammadparsa Khakpour, Fernando González Ibáñez, Maude Bordeleau, Katherine Picard, Leo Mckee-Reid, Benneth Ben-Azu and Laura Maggi. The …
Blocking Immune Cell Infiltration of the Central Nervous System to Tame Neuroinflammation in Amyotrophic Lateral Sclerosis
Publication alert! IALH Research Fellow Marie-Ève Tremblay has co-authored a research article entitled Blocking immune cell infiltration of the central nervous system to tame Neuroinflammation in Amyotrophic lateral sclerosis. Other authors include Stefano Garofalo, Germana Cocozza, Giovanni Bernardini, Julie Savage, Marcello Raspa, Eleonora Aronica, Richard M. Ransohoff, Angela Santoni, and Cristina Limatola. The article was …
Microglia as a Hub for Suicide Neuropathology: Future Investigation and Prevention Targets
[et_pb_section fb_built=”1″ admin_label=”section” _builder_version=”4.16″ global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_row admin_label=”row” _builder_version=”4.16″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||” theme_builder_area=”post_content”][et_pb_text admin_label=”Text” _builder_version=”4.16″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” global_colors_info=”{}” theme_builder_area=”post_content”]Publication Alert! IALH Research Fellow Marie-Ève Tremblay has co-authored a new research article entitled Microglia as a Hub for Suicide Neuropathology: Future Investigation and Prevention Targets. Other authors include Elisa …