hiPSC-Derived GRN-Deficient Astrocytes Delay Spiking Activity of Developing Neurons

IALH Research Fellow Stephanie Willerth (Engineering) has co-authored a new research article entitled hiPSC-derived GRN-deficient astrocytes delay spiking activity of developing neurons. Collaborating authors include Christopher Lee, Jonathan Frew, Nicholas L. Weilinger, Stefan Wendt, Wenji Cai, Stefano Sorrentino, Xiujuan Wu, Brian A. MacVicar, and Haakon B. Nygaard. The article was published in Neurobiology of Disease. …

Astrocytes Display Ultrastructural Alterations and Heterogeneity in the Hippocampus of Aged APP-PS1 Mice and Human Post-Mortem Brain Samples

IALH Research Fellow and co-lead of IALH’s Brain Health Research cluster Marie-Ève Tremblay has co-authored a new research article entitled Astrocytes display ultrastructural alterations and heterogeneity in the hippocampus of aged APP-PS1 mice and human post-mortem brain samples. Collaborating authors include Marie-Kim St-Pierre, Micaël Carrier, Fernando González Ibáñez, Mohammadparsa Khakpour, Marie-Josée Wallman, and Martin Parent. …

Blocking Immune Cell Infiltration of the Central Nervous System to Tame Neuroinflammation in Amyotrophic Lateral Sclerosis

Publication alert! IALH Research Fellow Marie-Ève Tremblay has co-authored a research article entitled Blocking immune cell infiltration of the central nervous system to tame Neuroinflammation in Amyotrophic lateral sclerosis. Other authors include Stefano Garofalo, Germana Cocozza, Giovanni Bernardini, Julie Savage, Marcello Raspa, Eleonora Aronica, Richard M. Ransohoff, Angela Santoni, and Cristina Limatola. The article was …