IALH Research Fellow Stephanie Willerth has published a new research article entitled Recent developments in 3D bioprinting for neural tissue engineering. Collaborating authors include Ruchi Sharma, Victor Allisson da Silva, and Maria Victoria Hangad. The article was published in Handbook of Neural Engineering.
Abstract:
Neural tissue engineering research develops appropriate ways of studying and treating neurological injuries and disorders. The nervous system consists of complex multilayer tissues with unique architectural characteristics. Accordingly, tissue-engineered scaffolds with complicated architectures with appropriate physicochemical properties must be designed that promote neural cell function and viability. Furthermore, such engineered neural tissue can replicate neurological diseases in vitro through technologies including organoid development, 3D bioprinting, and lab-on-a-chip systems. In particular, 3D bioprinting technology enables researchers to assemble multimaterial and cell-laden scaffolds in an efficient and effective fashion by producing neural tissues based on specifications contained in a digital file. 3D bioprinting can produce neural tissue models in a faster, more efficient, and personalized way. This effective technique allows for the high-throughput fabrication of architecturally well-defined 3D scaffolds seeded with neural cells. This chapter will cover the need for 3D printing of neural tissue models, their applications, and avenues for future work.
To read the full article, see https://doi.org/10.1016/B978-0-323-95730-4.00012-3