Publication alert! IALH Research Fellow Stephanie Willerth (Mechanical Engineering) has co-authored a new research article entitled Microfluidic Generation of Therapeutically Relevant Polycaprolactone (PCL) Microparticles: Computational and Experimental Approaches. Other authors include University of Victoria researchers Alejandro Forigua, Arash Dalili, Rebecca Kirsch and Katherine S. Elvira and the article was published in ACS Applied Polymer Materials. …
Category Archives: Brain Health
Longitudinal Changes in Grey Matter and Cognitive Performance Over Four Years of Healthy Aging
Publication alert! IALH Research Fellow Jodie Gawryluk and IALH Student Affiliates Ashleigh Parker and Heather Kwan have co-authored a new research article with Nicole Neufeld, and Erin Mazerolle entitled Longitudinal Changes in Grey Matter and Cognitive Performance Over Four Years of Healthy Aging. The article was published in Neuroimage: Reports. Abstract: Background: Normal aging is …
A 3D Analysis Revealed Complexe Mitochondria Morphologies in Porcine Cumulus Cells
Publication alert! IALH Research Fellow Marie-Ève Tremblay has co-authored a new research article entitled A 3D analysis revealed complexe mitochondria morphologies in porcine cumulus cells. Other authors include Amel Lounas, Ariane Lebrun, Isabelle Laflamme, Nathalie Vernoux, Julie Savage, Marc Germain & François J. Richard. The article was published in Scientific Reports. Abstract: In the ovarian …
Dynamic onset response of the internal carotid artery to hypercapnia is blunted in children compared with adults
Publication alert! IALH Research Fellow Kurt Smith has co-authored a new research article entitled Dynamic onset response of the internal carotid artery to hypercapnia is blunted in children compared with adults which was published in Physiological Reports. Other authors include Christine M. Tallon, Jack S. Talbot, Nia Lewis, Daniela Nowak-Flück, Mike Stembridge, Philip Ainslie …
Editorial: Natural Products as Drivers in Drug Development for Neurodegenerative Disorders
Publication alert! IALH Research Fellow Hector Caruncho has co-authored an article entitled Editorial: Natural products as drivers in drug development for neurodegenerative disorders with authors Joana Silva, Rebeca Alvariño, Márcia I. Goettert and Celso Alves. This editorial article was published in Frontiers. Excerpt: The prevalence of neurological disorders (NDs) is a large and increasing health …
The Future of Neuroimmunology Research for CNS Disease Therapeutics
Promising pharmacological targets and drug approaches for the treatment of diseases of the central nervous system (CNS) are emerging. Jerry Madukwe, the Editor-in-Chief of Trends in Pharmacological Sciences asked authors of the August 2022 special issue to reflect on the global challenges in the field and what they see as the future of neuroimmunology research …
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Density of TMEM119-Positive Microglial Cells in Postmortem Cerebrospinal Fluid as a Surrogate Marker for Assessing Complex Neuropathological Processes in the CNS
Publication alert! IALH Research Fellow Marie-Ève Tremblay has co-authored a new research article entitled Density of TMEM119-positive microglial cells in postmortem cerebrospinal fluid as a surrogate marker for assessing complex neuropathological processes in the CNS. Other authors include Simone Bohnert, Stefanie Trella, Ulrich Preiß, Helmut Heinsen, Michael Bohnert, Johann Zwirner, Camelia-Maria Monoranu and Benjamin Ondruschka. …
Manual versus automatic analysis of microglial density and distribution: a comparison in the hippocampus of healthy and lipopolysaccharide-challenged mature male mice
Publication alert! IALH Research Fellow Marie-Ève Tremblay has co-authored a new research article entitled Manual versus automatic analysis of microglial density and distribution: a comparison in the hippocampus of healthy and lipopolysaccharide-challenged mature male mice. Other authors include Mohammadparsa Khakpour, Fernando González Ibáñez, Maude Bordeleau, Katherine Picard, Leo Mckee-Reid, Benneth Ben-Azu and Laura Maggi. The …
Blocking Immune Cell Infiltration of the Central Nervous System to Tame Neuroinflammation in Amyotrophic Lateral Sclerosis
Publication alert! IALH Research Fellow Marie-Ève Tremblay has co-authored a research article entitled Blocking immune cell infiltration of the central nervous system to tame Neuroinflammation in Amyotrophic lateral sclerosis. Other authors include Stefano Garofalo, Germana Cocozza, Giovanni Bernardini, Julie Savage, Marcello Raspa, Eleonora Aronica, Richard M. Ransohoff, Angela Santoni, and Cristina Limatola. The article was …
Exploring the impact of community-based choral participation on cognitive function and well-being for persons with dementia: evidence from the Voices in Motion project
Publication alert! IALH Research Fellows André Smith, Debra Sheets and Stuart MacDonald have co-authored a research article with IALH Student Affiliate Cynthia McDowell, IALH Project Coordinator Carren Dujela and Nicholas Tamburri. The article, entitled Exploring the impact of community-based choral participation on cognitive function and well-being for persons with dementia: evidence from the Voices in …
Behavioral and Neural Activity-Dependent Recanalization of Plugged Capillaries in the Brain of Adult and Aged Mice
Publication alert! IALH Research Fellow Craig Brown has co-authored a research article entitled Behavioral and Neural Activity-Dependent Recanalization of Plugged Capillaries in the Brain of Adult and Aged Mice. Other authors include Patrick Reeson, Ben Schager, and Myrthe Van Sprengel. The article was published in Frontiers in Cellular Neuroscience. Abstract: The capillaries of the brain, …
Parameterizing Practice in a Longitudinal Measurement Burst Design to Dissociate Retest Effects From Developmental Change: Implications for Aging Neuroscience
Publication alert! IALH Research Fellow Stuart MacDonald has co-authored an article with Nicholas Tamburri and IALH Student Affiliate Cynthia McDowell. The article is entitled Parameterizing Practice in a Longitudinal Measurement Burst Design to Dissociate Retest Effects From Developmental Change: Implications for Aging Neuroscience and was published in Frontiers in Aging Neuroscience. Abstract: Background: In longitudinal …
Interindividual and Intraindividual Variability in Amnestic Mild Cognitive Impairment (aMCI) Measured with an Online Cognitive Assessment
Publication Alert! IALH Research Fellow Theone Paterson has co-authored an article entitled “Interindividual and intraindividual variability in amnestic mild cognitive impairment (aMCI) measured with an online cognitive assessment” in Journal of Clinical and Experimental Neuropsychology. Other authors include Annalise A. LaPlume, Sandra Gardner, Kathryn A. Stokes, Morris Freedman, Brian Levine, Angela K. Troyer, and Nicole …
Microglia as a Hub for Suicide Neuropathology: Future Investigation and Prevention Targets
[et_pb_section fb_built=”1″ admin_label=”section” _builder_version=”4.16″ global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_row admin_label=”row” _builder_version=”4.16″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||” theme_builder_area=”post_content”][et_pb_text admin_label=”Text” _builder_version=”4.16″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” global_colors_info=”{}” theme_builder_area=”post_content”]Publication Alert! IALH Research Fellow Marie-Ève Tremblay has co-authored a new research article entitled Microglia as a Hub for Suicide Neuropathology: Future Investigation and Prevention Targets. Other authors include Elisa …
Exercise and Hypercapnia Differentially Modify Ratios of Extracranial and Intracranial Pulsatility
[et_pb_section fb_built=”1″ admin_label=”section” _builder_version=”4.16″ global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_row admin_label=”row” _builder_version=”4.16″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_column type=”4_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||” theme_builder_area=”post_content”][et_pb_text admin_label=”Text” _builder_version=”4.17.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” hover_enabled=”0″ global_colors_info=”{}” theme_builder_area=”post_content” custom_margin=”|15px|||false|false” sticky_enabled=”0″]Publication Alert! IALH Research Fellow Kurt Smith has co-authored a new research article entitled Exercise and Hypercapnia Differentially Modify Ratios of Extracranial and Intracranial Pulsatility. Other authors …
Mitochondrial Dysfunction and Affective Disorders: Focus on Diet, Exercise, and Aging
Publication Alert! IALH Research Fellow Hector Caruncho has co-authored a book chapter entitled Mitochondrial dysfunction and affective disorders: Focus on diet, exercise, and aging. Other authors include Josh Allen and Lisa Kalynchuk. The chapter was published in Mitochondrial Dysfunction and Nanotherapeutics: Aging, Diseases, and Nanotechnology-Related Strategies in Mitochondrial Medicine. Abstract: Affective disorders, including major depression …
Experiences and perceptions of health care professionals making treatment decisions for older adults with memory loss: a qualitative systematic review protocol
Publication Alert! IALH Research Fellow Lorelei Newton has co-authored a review entitled “Experiences and Perceptions of Health Care Professionals Making Treatment Decisions for Older Adults with Memory Loss: A Qualitative Systematic Review Protocol ” Other authors include former IALH Student Affiliate Kimberly Shapkin, Karen MacKinnon, Esther Sangster-Gormley, and Jayna Holroyd-Leduc. The review was published in …
A Systematic Review of Neuroimaging Studies Comparing Individuals with Subjective Cognitive Decline to Healthy Controls
Publication Alert! IALH Research Fellow has co-authored a new research article entitled A Systematic Review of Neuroimaging Studies Comparing Individuals with Subjective Cognitive Decline to Healthy Controls with IALH Student Affiliates Ashleigh Parker, Lisa Ohlhauser, and Vanessa Scarapicchia. Other authors include Collette Smart and Cassandra Szoeke. The article is published in Journal of Alzheimer’s Disease. …
Studies of Twin Responses to Understand Exercise THerapy (STRUETH): cerebrovascular function
Publication Alert! IALH Research Fellow Kurt Smith has co-authored a new research article entitled Studies of Twin Responses to Understand Exercise THerapy (STRUETH): cerebrovascular function. Other authors include Hannah J. Thomas, Channa E. Marsh, Katrina J. Scurrah, Louise H. Naylor, and Daniel J. Green. The article was published in the Journal of Psychology. Abstract: We …
Personality Traits, Cognitive States, and Mortality in Older Adulthood
Publication Alert! IALH Research Fellows Andrea Piccinin and Scott Hofer, along with UVic Psychology doctoral graduate Tomiko Yoneda have co-authored a research article entitled Personality traits, cognitive states, and mortality in older adulthood. Other authors include Eileen Graham, Tristen Lozinski, David Bennett, Daniel Mroczek, Piccinin, & Graciela Muniz-Terrera. The article was published in Journal or …
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Present and Future of Microglial Pharmacology
Publication Alert! IALH Research Fellow Marie-Ève Tremblay has a review published in Trends in Pharmacological Sciences. The review is entitled “Present and future of microglial pharmacology”. Other authors include Eva Šimončičová, Elisa Gonçalves de Andrade, Haley A. Vecchiarelli, Ifeoluwa O.Awogbindin and Charlotte I.Delage. Highlights: Distinct microglial morphological, ultrastructural, and molecular states contribute contextually relevant functions …
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Postnatal Choline Supplementation Rescues Deficits in Synaptic Plasticity Following Prenatal Ethanol Exposure
Publication Alert! IALH Research Fellow Brain Christie (Division of Medical Sciences) has a new publication entitled Postnatal Choline Supplementation Rescues Deficits in Synaptic Plasticity Following Prenatal Ethanol Exposure. Other authors on this publication include Erin L. Grafe, Mira M.M. Wade, Claire E. Hodson, and Jennifer D. Thomas. Abstract: Prenatal ethanol exposure (PNEE) is a leading …
Psychotherapeutic Interventions for Dementia: a Systematic Review
Publication Alert! IALH Research Fellow Paweena Sukhawathanakul has published a systematic review with former IALH Director Holly Tuokko, Alexander Crizzle, Gary Naglie, and Mark J. Rapoport, entitled “Psychotherapeutic Interventions for Dementia: a Systematic Review”. The review was published in the Canadian Geriatrics Journal. Abstract: Background and Objectives: While a range of psychotherapeutic interventions is available …
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Maternal high-fat diet in mice induces cerebrovascular, microglial and long-term behavioural alterations in offspring
Publication Alert! IALH Research Fellow Marie-Ève Tremblay has published an article entitled “Maternal high-fat diet in mice induces cerebrovascular, microglial and long-term behavioural alterations in offspring.” Co-authors include Maude Bordeleau, Cesar H. Comin, Lourdes Fernández de Cossío, Chloé Lacabanne, Moises Freitas-Andrade, Fernando González Ibáñez, Joanna Raman-Nair, Michael Wakem, Mallar Chakravarty, Luciano da F. Costa and …
Functional near infrared spectroscopy activation during an executive function task differs between healthy older and younger adults
Publication Alert! IALH Faculty Affiliates Stuart MacDonald (Psychology) and Jodie Gawryluk (Psychology and Division of Medical Sciences) have published an article with Drew Halliday, Psychology students Heather Kwan and Vanessa Scarapicchia entitled “Functional near infrared spectroscopy activation during an executive function task differs between healthy older and younger adults” in Aging Brain. Abstract: Background Healthy …