In Vitro Electrophysiology

Regular aCSF

Click here to view our video on making regular artificial cerebrospinal fluid.

Cutting Solutions

Coming soon: how to make cutting solutions for electrophysiology!

Preparation Steps

Steps to follow at the beginning of your experiment.

Dissection

How to dissect brain from a rat or mouse.

Sectioning with a Ted Pella 1000 Vibratome

How to section a brain using a Ted Pella 1000 Vibratome.

Sectioning with a Precisionary Compresstome VF-310-0Z

How to section a brain into slices using a Precisionary Instruments compresstome!

Electrode Pulling

Things to consider when pulling pipettes for recording electrodes.

Image

Making Stimulation Electrodes

Coming soon: How to make stimulation electrodes!

Getting Started with pCLAMP

Coming soon: How to use pCLAMP!

Introduction to Field Recordings

Coming soon: Field Recordings for electrophysiology!

Data Analysis

Coming soon: How to analyze electrophysiology data!

Statistics with Python

Video covers a workflow for how to organize electrophysiology data for use in Python. Python code used in this video can be downloaded here.

Whole Cell Patch Clamp

Introduction to Whole Cell

Click here to view our full video on whole cell patch clamping.

Chapter 2 - Solution Preparation

Click here to view our video on solution prep for whole cell patch clamping.

Chapter 3 - Slice Preparation

Click here to view our video on slice preparation for whole cell patch clamping.

Chapter 4 - Rig Setup

Click here to view our video on rig setup for whole cell patch clamping.

Chapter 5 - Finding a Cell

Click here to view our video on finding a cell for whole cell patch clamping.

Chapter 6 - The Giga-Ohm Seal

Click here to view our video on the Giga-Ohm Seal for whole cell patch clamping.

Chapter 7 - Breaking the Patch

Click here to view our video on breaking the seal for whole cell patch clamping.

In Vivo Electrophysiology

Vernier Scale

Click here to watch our video discussing how to use a vernier scale!

Data Analysis

Coming soon: How to analyze electrophysiology data!

Statistics with Python

Video covers a workflow for how to organize electrophysiology data for use in Python. Python code used in this video can be downloaded here.